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Anticoagulants: Phenobarbital lowers the plasma amounts of dicumarol (title Earlier utilised: bishydroxycoumarin) and triggers a decrease in anticoagulant exercise as calculated with the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing improved metabolism and lessened anticoagulant response of oral anticoagulants (e.ADVE

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